Exhibit 1

JOINT FILING AGREEMENT
PURSUANT TO RULE 13d-1(k)

 

The undersigned acknowledge and agree that the foregoing statement on Schedule 13G is filed on behalf of each of the undersigned and that all subsequent amendments to this statement on Schedule 13G may be filed on behalf of each of the undersigned without the necessity of filing additional joint filing agreements. The undersigned acknowledge that each shall be responsible for the timely filing of such amendments, and for the completeness and accuracy of the information concerning it contained herein and therein, but shall not be responsible for the completeness and accuracy of the information concerning the others, except to the extent that it knows that such information is inaccurate.

 

Dated: April 6, 2017.

 

 

LUMIRA GP HOLDINGS CO.

 

  LUMIRA GP INC.
     
By: /s/ Vasco Larcina   By: /s/ Vasco Larcina
Name: Vasco Larcina    Name: Vasco Larcina 
Title:   VP Finance   Title:   VP Finance
     

LUMIRA CAPITAL GP, L.P.

 

  LUMIRA CAPITAL INVESTMENT MANAGEMENT INC.
     
By:  Lumira GP Holdings Co., its general partner   By: /s/ Vasco Larcina
    Name:  Vasco Larcina
By: /s/ Vasco Larcina   Title:    VP Finance
Name:  Vasco Larcina    
Title:    VP Finance    
     
     

LUMIRA CAPITAL II, L.P.

 

  LUMIRA CAPITAL II (INTERNATIONAL), L.P.
     
By:  Lumira Capital GP, L.P., its general partner   By:  Lumira Capital GP, L.P., its general partner
     
By:  Lumira GP Holdings Co., as general partner of  Lumira Capital GP, L.P.   By:  Lumira GP Holdings Co., as general partner of  Lumira Capital GP, L.P.  
     
By: /s/ Vasco Larcina   By: /s/ Vasco Larcina
Name:  Vasco Larcina   Name:  Vasco Larcina
Title:    VP Finance   Title:    VP Finance
     
     
BENJAMIN ROVINSKI    
     
By: /s/ Benjamin Rovinski